303 TYK2/JAK1 inhibition with PF-06700841 rapidly attenuates IL23/IL17 pathway genes and reverses the molecular phenotype in psoriasis
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the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Rac Inhibition Reverses the Phenotype of Fibrotic Fibroblasts
BACKGROUND Fibrosis, the excessive deposition of scar tissue by fibroblasts, is one of the largest groups of diseases for which there is no therapy. Fibroblasts from lesional areas of scleroderma patients possess elevated abilities to contract matrix and produce alpha-smooth muscle actin (alpha-SMA), type I collagen and CCN2 (connective tissue growth factor, CTGF). The basis for this phenomenon...
متن کاملthe relationship of wtc with communication apprehension and self-perceived communication competene in english and persian context
بیشتر تحقیقات پیشین در زمینه تمایل به برقراری ارتباط به رابطه آن با عوامل فردی چون سن، جنس، نوع شخصیت و... صورت گرفته است. در صورتی که مطالعات کمتری به بررسی رابطه تمایل به برقراری ارتباط زبان آموزان فارسی زبان با ترس از برقراری ارتباط و توانش خود ادراکانه آنها در برقراری ارتباط در محیط فارسی و انگلیسی انجام شده است. بر اساس نظریه الیس (2008) تمایل به برقراری ارتباط جایگاه مهمی در زمینه آموزش م...
15 صفحه اولMOLECULAR STUDY OF PKD1 & PKD2 GENES BY LINKAGE ANALYSIS AND DETERMINING THE GENOTYPE/PHENOTYPE CORRELATIONS IN SEVERAL IRANIAN FAMILIES WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
ABSTRACT Background: Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder with genetic heterogeneity. Up to three loci are involved in this disease, PKDI on chromosome 16p13.3, PKD2 on 4q21, and a third locus of unknown location. Methods: Here we report the first molecular genetic study of ADPKD and the existence oflocus heterogeneity for ADPKD in the Iranian populatio...
متن کاملResveratrol attenuates visfatin and vaspin genes expression in adipose tissue of rats with type 2 diabetes
Objective(s): Visfatin and vaspin are secreted by adipose tissue and play key roles in glucose homeostasis and subsequently are potential targets for diabetes treatment. Resveratrol (RVS) corrects insulin secretion and improves insulin sensitivity. We investigated the RVS effects on serum antioxidants, insulin and glucose levels, also visfatin and vaspin genes expression in adipose tissue of st...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.02.319